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Women's Health Weekly

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Cancer Vaccine



Immunological prevention of multigene cancer syndrome



February 10th, 2005

Researchers present strategies for the immunological prevention of multigene cancer syndrome in a recent issue of Cancer Research.

According to published research from Italy, "Vaccines effectively prevent the onset of tumors in transgenic mice carrying activated oncogenes; however, human tumors are caused by combined alterations in oncogenes and oncosuppressor genes. We evaluated the impact of prophylactic vaccines in HER-2/neu transgenic, p53 wild-type/null mice that succumb to an aggressive cancer syndrome comprising mammary and salivary gland carcinomas and rhabdomyosarcoma."

"A vaccine made of allogeneic mammary carcinoma cells expressing...


Source: Women's Health Weekly (2005-02-10)

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