Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Array CGH can identify genomic alterations in breast tumor subtypes
February 17th, 2005
Array comparative genomic hybridization can identify genomic alterations associated with breast cancer subtypes. In a recent study, researchers in the United States "performed high-resolution array comparative genomic hybridization with an array of 4,153 bacterial artificial chromosome clones to assess copy number changes in 44 archival breast cancers." "The tumors were flow sorted to exclude non-tumor DNA and increase our ability to detect gene copy number changes," explained L.W.M. Loo and coauthors at the Fred Hutchinson Cancer Research Center in Seattle. "In these tumors, losses were more frequent than gains, and gains in 1q and loss in 16q were...
Source: Women's Health Weekly (2005-02-17)
|
