Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cervical Cancer
Protein may have limited use as biomarker in cervical glandular lesions
February 17th, 2005
The tumor suppressor protein p16(INK4A) may have limited use as a biomarker in cervical glandular lesions, say pathologists. "A wide array of immunohistochemical markers have been evaluated with respect to their specificity in staining dysplastic cervical cells in cervical biopsies and cervical cytological smears. However, there is still a significant demand for better biomarkers to identify neoplastic cervical glandular and squamous epithelial cells precisely," wrote N. Murphy and colleagues, Coombe Women's Hospital, Dublin, Ireland. "The CDKN2A gene, located on chromosome 9p21, encodes ...p16(INK4A), which decelerates the cell cycle by inactivating...
Source: Women's Health Weekly (2005-02-17)
|
