Women's Health Weekly
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Chlamydiosis
CPAF is produced and immunogenic during human chlamydial infection
February 17th, 2005
Chlamydial proteasome/protease-like activity factor is produced and exhibits immunogenic activity during human chlamydial infection, University of Texas researchers report. J. Sharma and colleagues "previously identified a chlamydia-secreted protein (designated chlamydial proteasome/protease-like activity factor, or CPAF) in the cytosol of chlamydia-infected cells. Although CPAF is known to degrade host transcription factors required for major histocompatibility complex antigen expression in cultured cells, it is not clear whether CPAF is produced and maintains similar functions in humans infected with chlamydial organisms," the researchers said. ...
Source: Women's Health Weekly (2005-02-17)
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