Women's Health Weekly
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Breast Cancer
Acetyl-CoA carboxylase alpha gene is not a major cause of susceptibility
February 24th, 2005
The acetyl-CoA carboxylase alpha gene (ACCalpha) is not a major cause of breast cancer susceptibility, researchers report. "The identification of an interaction between BRCA1 and acetyl-CoA carboxylase alpha (ACCalpha), a key enzyme in lipid synthesis, led us to investigate the role of ACCalpha in breast cancer development, where it might contribute to the energy-sensing mechanisms of malignant transformation," wrote O.M. Sinilnikova and associates in a recent issue of the journal Carcinogenesis. "In order to investigate if certain ACCalpha alleles may be high-risk breast cancer susceptibility alleles, 37 extended breast and breast/ovarian...
Source: Women's Health Weekly (2005-02-24)
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