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Women's Health Weekly

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Breast Cancer



CYP1A1 gene modifies the relation between PCB exposure and breast cancer risk



February 24th, 2005

The cytochrome P-450 1A1 gene (CYP1A1) modifies the relation between PCB exposure and breast cancer risk, researchers at Yale University report.

According to published research from the United States, "Recent epidemiologic studies have suggested that genetic polymorphisms in the cytochrome P-450 1A1 gene (CYP1A1) may affect the relation between environmental exposure to polychlorinated biphenyls (PCBs) and breast cancer risk."

"The authors report results from a case-control study evaluating the potential effect of gene-environment interaction between CYP1A1 and serum PCB levels on breast cancer risk among Caucasian women in Connecticut. The study...


Source: Women's Health Weekly (2005-02-24)

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