Breast Cancer

Effect of ionizing radiation on nuclear proto-oncogenes determined

Published in Women's Health Weekly, February 24th, 2005

The effects of ionizing radiation on nuclear proto-oncogenes in breast cells have been determined.

"The identification of genes involved in breast cancer is of critical importance in understanding the pathogenesis of the disease," oncologists in New York explained. "Expression of the nuclear proto-oncogenes, c-myc, c-jun and c-fos, are indicative of early response events during cellular proliferation;" among them, "the c-myc oncogene has been found frequently overexpressed in breast cancer."

"In vitro systems allow us to test the sensitivity of human breast epithelial cells to different carcinogens, including ionizing radiation," noted G.M. Calaf and...

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Source: Women's Health Weekly (2005-02-24)

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