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Women's Health Weekly

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Breast Cancer



Study: Femara provides survival advantage vs. tamoxifen in adjuvant treatment



February 24th, 2005

Adjuvant use of Femara (letrozole tablets) in postmenopausal women with hormone receptor-positive early breast cancer demonstrated a significant 19% reduction in risk of relapse (p=0.003), especially reducing the risk that the cancer would spread to other parts of the body (distant metastases) by 27%, compared with the reductions offered by tamoxifen (p=0.006), according to an independent, international study presented by the International Breast Cancer Study Group.

The data, from the Breast International Group (BIG) 1-98 trial, result from a head-to-head comparison of Femara with tamoxifen in more than 8000 women treated at a median follow-up of 26 months.

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Source: Women's Health Weekly (2005-02-24)

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