Women's Health Weekly
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Cervical Cancer
Histidine triad gene intron 5 linked to severe cases
February 24th, 2005
Loss of heterozygosity in the histidine triad gene intron 5 is linked to more severe cases of cervical cancer. According to a study published in a recent issue of the British Journal of Cancer, "The presence of high-risk human papillomavirus, loss of heterozygosity on chromosome 3p and fragile histidine triad gene expression were assessed as potential markers of cancer and CIN progression in 83 cervical cancers and 74 cervical intraepithelial neoplasia grade 1 lesions." "Human papillomavirus type 16 was an indicator of vascular involvement in cancers. Loss of heterozygosity, especially in the fragile histidine triad gene intron 5, was an...
Source: Women's Health Weekly (2005-02-24)
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