Women's Health Weekly
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Coronary Artery Disease
The eNOS 4a/b polymorphism does not have a major impact on CAD
February 24th, 2005
Researchers conclude that the eNOS 4a/b polymorphism is not associated with preamature coronary artery disease (CAD) in white women. According to a study from Slovenia, "Endothelial nitric oxide synthase (eNOS) catalyzes the formation of nitric oxide (NO) which has vasodilatory, antithrombotic, antinflammatory and antiproliferative actions through which NO regulates blood pressure and modulates the process of atherosclerosis. Genetic polymorphism of the eNOS gene has been identified in several studies as a risk factor for cardiovascular diseases." "In this case-control study we examined a possible association of the polymorphism in intron 4 (4a/b) of...
Source: Women's Health Weekly (2005-02-24)
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