Women's Health Weekly
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Breast Cancer
CYP17 gene variant interactions affect breast density, possibly cancer risk
March 3rd, 2005
Interactions of a CYP17 gene variant with insulin levels and diet affect breast density and may affect breast cancer risk, study findings suggest. "Mammographic density is associated with increased breast cancer risk and is influenced by sex hormones. A T27C polymorphism (alleles A1 and A2, respectively) in the 5' promoter region of CYP17 may be associated with elevated sex hormone levels," wrote C.C. Hong and colleagues, Ontario Cancer Institute. They conducted "a cross-sectional study of 181 pre- and 173 postmenopausal women [in which they examined] the relationship of this polymorphism with mammographic density and other risk factors for breast...
Source: Women's Health Weekly (2005-03-03)
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