Women's Health Weekly
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Breast Cancer
Estrogen receptor genetic variants and cancer risk investigated
March 3rd, 2005
Researchers with the U.S. National Cancer Institute noted in a recent paper that "most breast cancer is not associated with a hereditary syndrome, occurs in postmenopausal women, and is estrogen and progesterone receptor-positive. "Estrogen exposure is an epidemiologic risk factor for breast cancer and estrogen is a potent mammary mitogen." The scientists "studied single nucleotide polymorphisms (SNPs) in estrogen receptors in 615 healthy subjects and 1,011 individuals with histologically confirmed breast cancer, all from New York City." B. Gold and colleagues "analyzed 13 SNPs in the progesterone receptor gene (PLR), 17 SNPs in...
Source: Women's Health Weekly (2005-03-03)
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