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Women's Health Weekly

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Breast Cancer



Identification of second breast cancer gene announced



March 3rd, 2005

SEQUENOM, Inc., (NASDAQ:SQNM) announced the discovery of genetic variations in the gene encoding the nuclear mitotic apparatus protein (NuMA) that affect breast cancer risk.

Published in the online early edition of the Proceedings of the National Academy of Sciences of the USA (PNAS), the study entitled "Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility" reports that individuals with a coding variation in the NuMA gene have more than a 2-fold higher risk of developing breast cancer than those without it. This risk is increased to more than 4-fold for cases with a family history of cancer.

The company...


Source: Women's Health Weekly (2005-03-03)

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