Women's Health Weekly
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Cancer Genetics
BRCA2-related protein repairs broken DNA
March 3rd, 2005
Much research has focused on how the BRCA2 gene influences breast cancer. Disease results when the gene produces a defective protein. But the normal function of this protein has also been mysterious. Now a new study on a BRCA2-related protein suggests that BRCA2 plays an important role in normal DNA repair. In a paper in the February 10, 2005, issue of Nature, Nikola Pavletich of the Memorial Sloan-Kettering Cancer Center, New York, and his colleagues showed that a BRCA2 homologue in the fungus Ustilago maydis helps another protein that is fundamentally important for DNA repair to load onto single-stranded DNA, a necessary event for its...
Source: Women's Health Weekly (2005-03-03)
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