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Women's Health Weekly

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Cancer Therapy



As2 O3 causes caspase-independent cell death in cervical cancer cells



March 3rd, 2005

A recent report shows As2 O3 causes caspase-independent cell death in human cervical cancer cells, researchers say.

According to a recent paper published in the journal Cancer Research, "Although mechanisms of arsenic trioxide (As2 O3 )-induced cell death have been studied extensively in hematologic cancers, those in solid cancers have yet to be clearly defined."

Y.H. Kang and colleagues at the Korea Institute of Radiological & Medical Science, Seoul, "showed that the translocation of apoptosis-inducing factor (AIF) from mitochondria to the nucleus is required for As2 O3...


Source: Women's Health Weekly (2005-03-03)

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