Women's Health Weekly
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Carcinogenesis
Findings describe new data in carcinogenesis research
March 3rd, 2005
Carcinogenesis research advances have been reported from Malaysia, Taiwan and the People's Republic of China. Study 1: Researchers in Malaysia have identified in a mouse model apoptosis-associated genes regulated in response to diethylstilbestrol (DES). "Studies with clastogenic carcinogen diethylstilbestrol resulted in a broad of spectrum of toxic and carcinogenic effects in humans and rodents, but the cellular and molecular mechanism(s) by which it induces cancer is not clear. To identify putative genetic targets for p53 in vivo, we applied the cDNA macroarray gene expression profiles associated with apoptosis by comparing p53+/- knockout mice and...
Source: Women's Health Weekly (2005-03-03)
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