Women's Health Weekly
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Atherosclerosis
Small-LDL particle link to endothelial dysfunction found in older women
March 10th, 2005
Hypertriglyceridemia-induced increase in small low-density lipoprotein particles is associated with endothelial dysfunction in postmenopausal women, according to a study from Japan. "Low concentrations of estrogen may decrease endothelial function in postmenopausal women. Elevated plasma triglycerides after menopause are frequently associated with a small, dense low-density lipoprotein (LDL) phenotype. Small LDL particles that are more susceptible to oxidation can also inhibit endothelium-dependent vasodilation," wrote A. Wakatsuki and colleagues, Kochi Medical School. In a cohort of 15 pre- and 41 postmenopausal women, the researchers investigated...
Source: Women's Health Weekly (2005-03-10)
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