Hormone Replacement Therapy

Changing chemistry helps explain estrogen threat to the heart

Published in Women's Health Weekly, March 10th, 2005

A piece of the topical puzzle of how estrogen goes from protecting women from heart disease to apparently increasing their risk later in life may have been found.

Medical College of Georgia researchers have found changes in blood vessel chemistry that may explain the dramatic flip-flop in estrogen's function that occurs in older women, taking it from a dilator of vessels to a potentially dangerous constrictor.

Richard White, a pharmacologist at MCG in Augusta, Georgia, presented the findings at the American Heart Association's Second International Conference on Women, Heart Disease and Stroke in Orlando, Florida, February 16-19, 2005.

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Source: Women's Health Weekly (2005-03-10)

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