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Women's Health Weekly

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Business Update



Glaxo makes $1.0 million payment, starts phase 2 studies of oral platelet drug



March 10th, 2005

Ligand Pharmaceuticals Incorporated (LGND) announced that the company has earned a $1 million milestone payment from GlaxoSmithKline (GSK) with that company's commencement of phase 2 trials of SB-497115, an oral, small molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets.

If the drug ultimately is approved and marketed, Ligand could receive double-digit royalties on product sales.

Thrombocytopenia (decreased platelet count) is a common side effect of many types of chemotherapy and can lead to uncontrolled bleeding, thus representing a significant problem in the...


Source: Women's Health Weekly (2005-03-10)

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