Women's Health Weekly
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Cancer Genetics
BRCA1 mutations estimated to be carried by over half a million U.S. Caucasians
March 10th, 2005
Stanford University researchers have estimated that over half a million Caucasians in the U.S. carry BRCA1 gene mutations. A.S. Whittemore and colleagues said, "Data from several countries indicate that 1 to 2% of Ashkenazi Jews carry a pathogenic ancestral mutation of the tumor suppressor gene BRCA1. However, the prevalence of BRCA1 mutations among non-Ashkenazi Whites is uncertain. "We estimated mutation carrier prevalence in U.S. non-Hispanic Whites, specific for Ashkenazi status, using data from two population-based series of San Francisco Bay Area patients with invasive cancers of the breast or ovary, and data on breast and ovarian cancer risks...
Source: Women's Health Weekly (2005-03-10)
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