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Uterine Cancer

Most minimal uterine serous carcinomas involve an endometrial polyp

Published in Women's Health Weekly, March 17th, 2005

Most minimal uterine serous carcinomas involve an endometrial polyp, Yale University pathologists have determined.

"The term 'minimal uterine serous carcinoma' has been proposed to include serous carcinomas with invasion limited to the endometrium (superficial serous carcinoma), and those without stromal invasion (intraepithelial serous carcinoma or endometrial intraepithelial carcinoma). Both lesions display similar cytological and immunohistochemical profiles of a typical invasive serous carcinoma with a high nuclear grade and an overexpression of mutant p53 protein," said P. Hui and colleagues.

They "studied the clinicopathologic features of 40...

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