Women's Health Weekly
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Breast & Prostate Cancer
ICAM gene region is breast and prostate cancer susceptibility locus
March 17th, 2005
The ICAM gene region is the breast and prostate cancer susceptibility locus. According to recent research from the United States, "We conducted a large-scale association study to identify genes that influence nonfamilial breast cancer risk using a collection of German cases and matched controls and >25,000 single nucleotide polymorphisms located within 16,000 genes. "One of the candidate loci identified was located on chromosome 19p13.2 [odds ratio (OR)=1.5, P=0.001]. The effect was substantially stronger in the subset of cases with reported family history of breast cancer (OR=3.4, P=0.001)." "The finding was subsequently...
Source: Women's Health Weekly (2005-03-17)
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