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Women's Health Weekly

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Breast Cancer Risk Factors



Integrin beta(3) Leu33Pro polymorphism may increase breast cancer risk by age 45



March 17th, 2005

The integrin beta(3) Leu33Pro polymorphism may increase breast cancer risk by age 45.

According to recent research published in the journal Breast Cancer Research and Treatment, "A functional polymorphism at codon 33 (leucine-to-proline, Leu33Pro)/nucleotide 1565 (T-to-C, T1565C) of the integrin beta(3) has been hypothesized to increase the risk of breast cancer and its metastasis. Three studies have been conducted up to date and the results were contradictory.

"We used a large population-based age-matched case-control study in German Caucasian women by the age of 50 years to assess breast cancer risk associated with this polymorphism, taking...


Source: Women's Health Weekly (2005-03-17)

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