Women's Health Weekly
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Breast Cancer Vaccines
Researchers detail new studies and findings in the area of breast cancer vaccines
March 17th, 2005
Breast cancer vaccines data are the focus of recent research from the United States and Italy. Study 1: Vaccination against mutated epidermal growth factor receptor may boost immune responses against breast cancer. "Mutated epidermal growth factor receptor (EGF-RvIII, DeltaEGF-R, and de2-7 EGF-R) is the result of an 801-bp deletion within the extracellular domain of wild-type EGF-R and is expressed by breast carcinomas, but not by normal breast tissues. EGF-RvIII is expressed both on the surface and in the cytoplasm of tumor cells. Thus, EGF-RvIII is a potential tumor-specific target for both antibodies and T cells. However, it is not known whether...
Source: Women's Health Weekly (2005-03-17)
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