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Women's Health Weekly

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Chlamydia



Surfactant protein D inhibits Chlamydia trachomatis infection



March 17th, 2005

Surfactant protein D is present in the human female reproductive tract and inhibits Chlamydia trachomatis infection.

"Surfactant protein D (SP-D) is a lung collectin involved in innate host defense mechanisms in the lung. SP-D is also expressed at other mucosal sites throughout the human body. In the present study, we show that SP-D mRNA and protein are expressed in the human female reproductive tract. SP-D protein was localized in the apical portion of the reproductive epithelial cells. We also demonstrate that endometrial and endocervical cell lines and primary endocervical cells in culture produce SP-D mRNA and protein," scientists in the United States...


Source: Women's Health Weekly (2005-03-17)

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