Women's Health Weekly
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Animal Models
Genetic mouse models of endometriosis and endometrioid ovarian cancer developed
March 17th, 2005
Researchers with the Massachusetts Institute of Technology have developed mouse models of endometriosis and endometrioid ovarian cancer. "Epithelial ovarian tumors present a complex clinical, diagnostic, and therapeutic challenge because of the difficulty of early detection, lack of known precursor lesions, and high mortality rates," D.M. Dinulescu and colleagues wrote. "Endometrioid ovarian carcinomas are frequently associated with endometriosis, but the mechanism for this association remains unknown." Reporting in Nature Medicine, the researchers described "the first genetic models of peritoneal endometriosis and endometrioid ovarian...
Source: Women's Health Weekly (2005-03-17)
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