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Women's Health Weekly

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Assisted Reproduction



Anti-hyaluronidase oligosaccharide analyzed, influence on polyspermy revealed



March 24th, 2005

According to recent research from Japan published in the journal Biology of Reproduction, anti-hyaluronidase oligosaccharide derived from chondroitin sulfate A effectively reduces polyspermy during in vitro fertilization of porcine oocytes.

"The present study was conducted to examine the effects of chondroitin sulfate A-derived oligosaccharide (ChSAO) on hyaluronidase activity and in vitro fertilization (IVF) parameters," wrote H. Tatemoto and colleagues, University of Ryukyus.

"The activity of hyaluronidase extracted from preincubated boar sperm was completely blocked by ChSAO at concentrations of 10 mcg/ml or higher. After in vitro...


Source: Women's Health Weekly (2005-03-24)

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