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Women's Health Weekly

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Assisted Reproduction



Cetrorelix and leuprolide acetate comparably inhibit premature LH surges



March 24th, 2005

Data from an open label, randomized, multicenter study indicate that cetrorelix, a luteinizing hormone-releasing hormone antagonist, and leuprolide acetate are similar in safety and effectiveness for inhibiting premature surges in luteinizing hormone (LH).

The comparison was made with and without the supplementation of recombinant human luteinizing hormone in women treated with cetrorelix.

M.V. Sauer and colleagues, Columbia Presbyterian Medical Center, New York, reported, "Normo-ovulatory women (n=74) undergoing ovarian stimulation prior to intracytoplasmic sperm injection were treated with leuprolide acetate (n=25) before ovarian stimulation with...


Source: Women's Health Weekly (2005-03-24)

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