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Women's Health Weekly

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Cervical Cancer



MTHFR, MS variants in folate metabolic pathway linked to reduced CIN 2/3 risk



March 31st, 2005

Study data indicate that polymorphisms of methylenetetrahydrofolate reductase and methionine synthase genes are associated with reduced risk of cervical intraepithelial neoplasia 2 or 3 in women with adequate folic acid intake.

According to University of Alabama, Birmingham, nutrition scientists, "The role of nutrient-related genetic susceptibility factors for precancerous lesions is gaining attention."

They "conducted a study to examine associations between polymorphisms in folate pathway coenzymes (methylenetetrahydrofolate reductase [MTHFR] and methionine synthase [MS]) and cervical intraepithelial neoplasia (CIN) 2 or 3 in a population exposed to...


Source: Women's Health Weekly (2005-03-31)

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