Women's Health Weekly
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Animal Models
SIV macaque model may help elucidate antibody response to HIV in breast milk
March 31st, 2005
The rhesus macaque model of simian immunodeficiency virus (SIV) may help researchers better understand the role of antibody response to HIV in breast milk. "As a model of breast milk transmission of HIV, we characterized humoral immune responses in the milk and plasma of 14 female rhesus macaques with suckling infants," reported J. Rychert and colleagues, Louisiana State University. "Total immunoglobulin (Ig) levels in plasma and milk were similar in all females and could not be correlated with transmission to the infant. These females, however, had elevated milk IgG levels and decreased milk IgA levels as compared with levels in seronegative...
Source: Women's Health Weekly (2005-03-31)
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