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Women's Health Weekly

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Atherosclerosis



Mouse gene turned on by fatty food linked to human heart-disease gene



April 7th, 2005

There is more evidence linking a high-fat diet to heart disease. An international research team has identified a gene that interacts with environmental factors, such as diet, to influence atherosclerosis susceptibility.

Atherosclerosis - the hardening of the arteries through deposition of cholesterol in the arterial wall - is the disease basis for coronary heart disease, the leading cause of death in the Western world.

As reported in Nature Genetics, the team, jointly led by Dr. Xiaosong Wang of The Jackson Laboratory and Dr. Jacob Lagercranz of Sweden's Karolinska Institute, has identified that Ox40l is a gene that makes C57BL/6J mice...


Source: Women's Health Weekly (2005-04-07)

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