Oncology
VEGF receptor inhibition impairs mammary tumor growth in mice
Published in Women's Health Weekly, April 7th, 2005
According to recent research published in the journal Oncogene, "cancer growth and progression is often critically influenced by the production of vascular endothelial growth factor (VEGF), a key mediator of angiogenesis. VEGF produced by tumor cells stimulates endothelial cell growth through the binding and activation of the KDR/Flk-1 receptor (VEGFR-2) on endothelial cells."
"Recently, some human breast cancer epithelial cells have been shown to express VEGF receptors, suggesting a potential autocrine-mediated growth stimulation of a subset of cancers by VEGF," said J.I. Huh and...
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