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Women's Health Weekly

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Breast Cancer



B7-H4 protein expression is almost ubiquitous in ductal and lobular disease



April 7th, 2005

B7-H4 protein expression is almost ubiquitous in ductal and lobular breast cancer, report pathologists.

This suggests B7-H4 is an important factor in the disease.

Barbara Tringler, University of Colorado Health Sciences Center, Denver, and colleagues there and with diaDexus, Inc., South San Francisco, California, "[investigated] the expression of B7-H4 protein, a member of the B7 family that is involved in the regulation of antigen-specific immune responses, in normal breast and in primary and metastatic breast carcinomas."

According to their report, "Archival formalin-fixed tissue blocks from breast cancers and normal somatic...


Source: Women's Health Weekly (2005-04-07)

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