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Women's Health Weekly

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Breast Cancer



Inducible nitric oxide synthase associated with breast cancer in irradiated rats



April 7th, 2005

According to a recent study, nitric oxide produced by inducible nitric oxide synthase is associated with mammary tumorigenesis in irradiated rats.

"This study evaluated whether nitric oxide (NO) derived from nitric oxide synthase (NOS) induced by radiation is associated with tumorigenesis in the mammary glands," investigators in Japan reported.

"When rats were exposed to whole-body irradiation with gamma-rays (1.5 Gy) immediately after weaning and then treated with diethylstilbestrol, as an irradiated control, the tumor incidence (85%) was increased 7.6-fold in comparison with that (11.1%) of the non-irradiated control," explained H. Inano and...


Source: Women's Health Weekly (2005-04-07)

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