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Women's Health Weekly

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Breast Cancer



Protein expression profiling identifies disease subclasses, predicts prognosis



April 7th, 2005

According to a study published recently in the journal Cancer Research, "Breast cancer is a heterogeneous disease whose evolution is difficult to predict by using classic histoclinical prognostic factors.

"Prognostic classification can benefit from molecular analyses such as large-scale expression profiling."

J. Jacquemier and colleagues, of France's INSERM UMR599 in Marseilles, reported, "Using immunohistochemistry on tissue microarrays, we have monitored the expression of 26 selected proteins in-more than 1,600 cancer samples from 552 consecutive patients with early breast cancer. Both an unsupervised approach and a new supervised method...


Source: Women's Health Weekly (2005-04-07)

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