Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Stat5 promoted homotypic adhesion and inhibited invasiveness of breast cancer
April 7th, 2005
According to research from the United States, Stat5 promoted homotypic adhesion and inhibited invasiveness of human breast cancer cells. "Signal transducer and activator of transcription-5 (Stat5) mediates prolactin (PRL)-induced differentiation and growth of breast epithelial cells," said A.S. Sultan and colleagues of Georgetown University. "We have recently identified active Stat5 as a tumor marker of favorable prognosis in human breast cancer, and determined that Stat5 activation is lost during metastatic progression. Here we provide novel evidence for an invasion-suppressive role of Stat5 in human breast cancer." "Activation...
Source: Women's Health Weekly (2005-04-07)
|
