Women's Health Weekly
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Cancer Genetics
Inhibiting angiotensin II may prevent or treat breast cancer
April 7th, 2005
A study from Singapore suggests that blocking angiotensin I-converting enzyme and/or the angiotensin II type 1 receptor, and thus inhibiting the effect of angiotensin II, may be a strategy to prevent or treat breast cancer. "Angiotensin II is converted from its precursor by angiotensin I-converting enzyme (ACE) and has been shown to mediate growth in breast cancer cell lines via ligand-induced activity through the angiotensin II type 1 receptor (AGTR1)," explained W.P. Koh and colleagues, National University of Singapore. "Earlier we showed that women with the low activity genotype of the ACE gene have a statistically significantly (about 50%)...
Source: Women's Health Weekly (2005-04-07)
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