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Women's Health Weekly

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Cardiology



Recent findings in cardiology described



April 7th, 2005

Cardiology research advances have been reported from the United Kingdom and United States.

Study 1: Sample size, power calculations, and their implications for the cost of thorough studies of drug induced QT interval prolongation

According to a study from England, "Regulatory authorities require new drugs to be investigated using a so-called 'thorough QT/QTc study' to identify compounds with a potential of influencing cardiac repolarization in man. Presently drafted regulatory consensus requires these studies to be powered for the statistical detection of QTc interval changes as small as 5 ms. Since this translates into a noticeable drug development...


Source: Women's Health Weekly (2005-04-07)

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