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Women's Health Weekly

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Adverse Drug Reaction



Fluoxetine-induced changes in sexual arousal not mediated by tactile sensation



April 7th, 2005

According to a study from the United States, "Sexual side effects resulting from serotonin specific reuptake inhibitors (SSRIs) use may be mediated by a number of peripheral mechanisms, including alterations in tactile sensitivity.

"It was hypothesized that sexual difficulties resulting from SSRI use arise in part from an oversensitivity or undersensitivity of tactile sensation."

P. Frohlich and C.A. Meston of the University of Texas Psychology Department examined "tactile sensitivity ...on the index finger and lower lip in clinically depressed women at baseline (premedication), week 1, week 4, and week 8 of drug treatment (fluoxetine group n=12,...


Source: Women's Health Weekly (2005-04-07)

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