Obstetrics
Genetic factors leading to hydatidiform moles can be modulated by other factors
Published in Women's Health Weekly, April 14th, 2005
R. Slim and colleagues, Montreal General Hospital, said, "We previously mapped a maternal recessive locus responsible for familial hydatidiform moles (HMs) to 19q13.4. The candidate region has recently been narrowed down to 1.1 megabases.
"Here, we report the segregation of alleles at 18 genetic markers, including nine new ones, from the HMs candidate region in a recently reported consanguineous family. In this family, five affected women had a total of seven HMs, three miscarriages, and three normal children."
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