Cardiovascular Disease

Preventing CVD may ameliorate some adverse effects of APOE genotype

Published in Women's Health Weekly, April 14th, 2005

Preventing cardiovascular disease in women as they age may reduce some of the adverse effects that the apolipoprotein E genotype has on cognitive function.

"The apolipoprotein E (APOE) e4 allele increases risk of Alzheimer disease and cardiovascular diseases. We examined APOE genotypes alone or combined with cardiovascular conditions in relation to cognitive function in 4,227 Nurses' Health Study participants, 70-80 years old," said J.E. Kang and colleagues at Harvard University's Brigham and Women's Hospital.

"From 1995 to 2001, and again 2 years later, participants received telephone cognitive assessments of general cognition, category fluency,...

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Source: Women's Health Weekly (2005-04-14)

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