Women's Health Weekly
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Adverse Drug Reaction
Anticonvulsant drug poses greater birth-defect risk than suspected
April 14th, 2005
Use of the anticonvulsant drug valproate during pregnancy may pose a significantly great risk of birth defects than other antiseizure medications. In the March 22, 2005, issue of Neurology, researchers from the North American AED (Antiepileptic Drug) Pregnancy Registry at Massachusetts General Hospital (MGH) reported that women taking valproate alone had a 4-fold increased risk of having a child with a major malformation, compared with the risk among women taking other anticonvulsants. "The basic message for women who take valproate is to plan ahead if they want to have children. Discuss the risks with their physician and consider taking...
Source: Women's Health Weekly (2005-04-14)
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