Women's Health Weekly
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Cancer Genetics
Double-strand break repair gene variants not linked to breast or ovarian cancer
April 21st, 2005
According to a report from Australia, "Deficiencies in DNA repair have been hypothesized to increase cancer risk and excess cancer incidence is a feature of inherited diseases caused by defects in DNA damage recognition and repair." P.M. Webb and colleagues, PO Royal Brisbane Hospital, University of Queensland, "investigated, using a case-control design, whether the double-strand break repair gene polymorphisms RAD51 5' untranslated region -135 G > C, XRCC2 R188H G > A, and XRCC3 T241M C > T were associated with risk of breast or ovarian cancer in Australian women. "Sample sets included 1,456 breast cancer cases and 793 age-matched controls...
Source: Women's Health Weekly (2005-04-21)
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