Women's Health Weekly
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Anorexia Nervosa
Fenfluramine accelerates weight loss from activity-based anorexia
April 28th, 2005
Fenfluramine treatment in female rats accelerates the weight loss associated with activity-based anorexia. "Serotonin plays an important role in controlling food intake and regulating body weight. Thus, altered serotonergic function may be involved in the etiology of anorexia nervosa. To investigate this hypothesis, we examined whether activation of the serotonin system increases the severity of activity-based anorexia, an animal model of anorexia nervosa in which food-restricted rats are housed with access to running wheels. This paradigm promotes symptoms of anorexia nervosa, including hypophagia, hyperactivity, and weight loss," researchers in the United States...
Source: Women's Health Weekly (2005-04-28)
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