Women's Health Weekly
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Breast Cancer
Extracellular matrix plays key role in metastasis
April 28th, 2005
The extracellular matrix plays a key role in breast tumor metastasis. In a recent study from Australia, a "clinically relevant model of spontaneous breast cancer metastasis to multiple sites, including bone, was characterized and used to identify genes involved in metastatic progression." "The metastatic potential of several genetically related tumor lines was assayed using a novel real-time quantitative RT-PCR assay of tumor burden," explained B.L. Eckhardt and coauthors at the Peter MacCallum Cancer Centre in Melbourne. "Based on this assay, the tumor lines were categorized as nonmetastatic (67NR), weakly metastatic to lymph node (168FARN) or lung...
Source: Women's Health Weekly (2005-04-28)
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