Women's Health Weekly
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Breast Cancer
MTHFR 677T variant/low folate associated with increased risk of breast cancer
April 28th, 2005
The MTHFR 677T variant allele and low dietary folate is associated with an increased risk of breast cancer. According to recent research published in the journal Cancer Research, "Accumulating evidence from epidemiologic studies suggests that risk of breast cancer is reduced in relation to increased consumption of folate and related B vitamins. "We investigated independent and joint effects of B vitamin intake as well as two polymorphisms of a key one-carbon metabolizing gene [i.e., methylenetetrahydrofolate reductase (MTHFR) 677C>T and I1298A>C] on breast cancer risk. The study uses the resources of a population-based case-control...
Source: Women's Health Weekly (2005-04-28)
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