Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Research
Spatially distinct binding of Cdc42 to key effector proteins studied
April 28th, 2005
Spatially distinct binding of Cdc42 to PAK1 and N-WASP has been studied in breast carcinoma cells. According to recent research published in the journal Molecular and Cellular Biology, "While a significant amount is known about the biochemical signaling pathways of the Rho family GTPase Cdc42, a better understanding of how these signaling networks are coordinated in cells is required. In particular, the predominant subcellular sites where GTP-bound Cdc42 binds to its effectors, such as p21-activated kinase 1 (PAKI) and N-WASP, a homolog of the Wiskott-Aldritch syndrome protein, are still undetermined. "Recent fluorescence resonance energy...
Source: Women's Health Weekly (2005-04-28)
|
