Diagnostics

Breast carcinoma: Persistent ITC in marrow suggests greater chance of recurrence

Published in Women's Health Weekly, April 28th, 2005

In breast carcinoma, persistence of isolated tumor cells (ITCs) in bone marrow (BM) suggests greater chance of recurrence.

"The prognostic significance of ITCs in bone marrow from patients with breast carcinoma at the time of their primary diagnosis recently has been confirmed by a large pooled analysis. If the persistence of ITCs after adjuvant therapy confers a similar risk for recurrence, then it would be an indication to consider second," researchers in Germany reported.

"The authors analyzed BM aspirates front 228 patients during recurrence-free follow-up at a median interval ± standard deviation (SD) of 21.3 ± 29.1 months after a...

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Source: Women's Health Weekly (2005-04-28)

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