Women's Health Weekly
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Adverse Drug Reaction
Effects of prenatal exposure to AZT on CNS investigated
April 28th, 2005
According to a study from Italy, "Zidovudine (AZT) is the main therapeutic agent against HIV vertical transmission and is routinely administered to seropositive pregnant women and their newborns. "Toxicity after chronic administration as well as cytogenetic effects following developmental AZT exposure has been reported. Furthermore, recent animal data indicate alterations of several behavioral endpoints during the entire lifespan of mice and rats after developmental AZT exposure." A. Venerosi and colleagues, Ist Super Sanita, Rome, "investigated specific central nervous system (CNS) effects of AZT administration during pregnancy on the...
Source: Women's Health Weekly (2005-04-28)
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