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Women's Health Weekly

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Breast Cancer



Decreased activity in TGF-beta pathway linked to increased disease risk



May 5th, 2005

Decreased activity within the transforming growth factor beta (TGF-beta) pathway is associated with increased breast cancer risk, researchers report.

The study, by researchers at Northwestern Memorial Hospital in Chicago and Northwestern University's Robert H. Lurie Comprehensive Cancer Center and published in the April 15, 2005, Cancer Research journal, is the first aimed at determining whether various combinations of two naturally-occurring variants of the TGF-beta pathway may predict breast cancer risk. It is also the first study assessing a cancer-related pathway by means of two functionally-relevant variants.

Blood tests were performed on...


Source: Women's Health Weekly (2005-05-05)

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